BackgroundAs moral case deliberations (MCDs) have increasingly been implemented in health care institutions as a form of ethics support, it is relevant to know whether and how MCDs actually contribute to positive changes in care. Insight is needed on what actually happens in daily care practice following MCD sessions. This study aimed at investigating the impact of MCD and exploring how ‘impact of MCD’ should be conceptualized for future research.MethodsA multiple-case study was conducted in a care organization for people with (...) intellectual disabilities and/or acquired brain injury, by observing MCD sessions as ‘cases’, followed by interviews with health care professionals concerning the follow-up to these cases, and a focus group with involved MCD facilitators. A conceptual scheme concerning the possible impact formed the basis for analysis: (1) individual moral awareness; (2) the actions of health care professionals; (3) collaboration among health care professionals; (4) the concrete situation of the client; (5) the client’s quality of care and life; (6) the organizational and policy level.ResultsAccording to interviewees, their moral awareness and their collaboration, both among colleagues and with clients’ relatives, improved after MCD. Perceived impact on client situation, quality of care/life and the organizational level varied among interviewees or was difficult to define or link to MCD. Three aspects were added to the conceptual scheme concerning the impact of MCD: (a) preparations and expectations prior to the MCD session; (b) a translational step between the conclusions of the MCD session and practical events in the following period, and (c) collaboration with clients’ relatives. A negative impact of MCD was also found on misunderstandings among participants and disappointment about lack of follow-up.ConclusionsConcretizing and conceptualizing the ‘impact’ of MCD is complicated as many factors play a role either before or during the transition from MCD to practice. It is important to consider ‘impact’ in a broad sense and to relate it to the goals and context of the MCD in question. Future studies in this field should pay additional attention to the preparations, content and process involved in ethics support, including clients’ and relatives’ experiences. (shrink)

We apply an online optimization process based on machine learning to the production of Bose-Einstein condensates. BEC is typically created with an exponential evaporation ramp that is optimal for ergodic dynamics with two-body s-wave interactions and no other loss rates, but likely sub-optimal for real experiments. Through repeated machine-controlled scientific experimentation and observations our ’learner’ discovers an optimal evaporation ramp for BEC production. In contrast to previous work, our learner uses a Gaussian process to develop a statistical model of the (...) relationship between the parameters it controls and the quality of the BEC produced. We demonstrate that the Gaussian process machine learner is able to discover a ramp that produces high quality BECs in 10 times fewer iterations than a previously used online optimization technique. Furthermore, we show the internal model developed can be used to determine which parameters are essential in BEC creation and which are unimportant, providing insight into the optimization process of the system. (shrink)

The criminal law presently distinguishes between actions and omissions, and only rarely proscribes failures to avert consequences that it would be an offense to bring about. Why? In recent years it has been persuasively argued by both Glover and Bennett that, celeris paribus, omissions to prevent a harm are just as culpable as are actions which bring that harm about. On the other hand, and acknowledging that hitherto “lawyers have not been very successful in finding a rationale for it,” Tony (...) Honoré has sought to defend the law's differential treatment. He proposes a “distinct-duties theory” that in addition to the general duties we owe to everyone, we also owe distinct duties to a more limited collection of people and associations, specified by features of our relationship with them. Where a distinct duty holds, breach by omission may well be no better than breach by positive action. But absent a distinct duty, omissions, per Honoré, are less culpable. They are mere failures to intervene and improve or rectify things, whereas actions are positive interventions which make things worse. And, thus, the law has good reason to differentiate between them. (shrink)

В работе рассматриваются некоторые актуальные аспекты творчества великих философов, писателей и поэтов - тех мыслителей, которые наиболее убедительно продемонстрировали генетическую связь философии и литературы.

Evolutionary developmental biology (evo-devo) has undergone dramatic transformations since its emergence as a distinct discipline. This paper aims to highlight the scope, power, and future promise of evo-devo to transform and unify diverse aspects of biology. We articulate key questions at the core of eleven biological disciplines—from Evolution, Development, Paleontology, and Neurobiology to Cellular and Molecular Biology, Quantitative Genetics, Human Diseases, Ecology, Agriculture and Science Education, and lastly, Evolutionary Developmental Biology itself—and discuss why evo-devo is uniquely situated to substantially improve (...) our ability to find meaningful answers to these fundamental questions. We posit that the tools, concepts, and ways of thinking developed by evo-devo have profound potential to advance, integrate, and unify biological sciences as well as inform policy decisions and illuminate science education. We look to the next generation of evolutionary developmental biologists to help shape this process as we confront the scientific challenges of the 21st century. (shrink)

Positive public perceptions of academic quality and professional ethics are critical to the long-term legitimacy of American colleges and universities. Faculty codes of conduct are one mechanism whereby the professoriate can define acceptable practice, exercise social control, and maintain public confidence in higher education, yet the drivers of their adoption are not well understood. Building upon previous research into such organizational behavior by institutional type, this study examined the prevalence and content of publicly posted faculty codes of conduct within an (...) organizational field of institutions that share a common religious identity but differ in their institutional types and employment structures. Faculty handbooks from American member institutions of the Council for Christian Colleges & Universities, an international association of faith-based institutions, were gathered and analyzed. Although only 27% of CCCU member institutions in the U.S. publicly posted faculty codes of conduct, the average number of tenets present in each code was higher than suggested by previous research. Study findings also revealed that membership category, institutional type, and employment structures influence the content of faculty codes of conduct, indicating that isomorphic pressures operate within this particular organizational field. The piece concludes by commending publicly posted codes of conduct as an affirmation of the personal responsibility, fairness, and care exercised by ethical professionals in the academy. (shrink)

We used computer simulations to study the possible role of the dispersion of cellular coupling, refractoriness or both, in the mechanisms underlying cardiac arrhythmias. Local ischemia was first assumed to induce cell to cell dispersion of the coupling resistance (Case 1), refractory period (Case 2), or both of them (Case 3). Our numerical experiments based on the van Capelle and Durrer model showed that vortices could not be induced by cell to cell variations. With cellular properties dispersed in a patchy (...) way within the ischemic zone, a single activation wave could give rise to abnormal activities. This demonstrates the stability of the wave front under small inhomogeneities. Probabilities of reentry, estimated for the three cases cited above showed that a severe alteration of the coupling resistance may be an important factor in the genesis of reentry. Moreover, use of isochronal maps revealed that vortices were both stable and sustained with an alteration of the coupling alone or combined with a reduction of the action potential duration. Conversely, simulations with reduction of the refractoriness alone, inducing only transient patterns, could exhibit functionally determined reentries. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Aristotle on the Etruscan Robbers:A Core Text of "Aristotelian Dualism"Abraham P. Bos (bio)1. A Non-Platonic Dualism in Aristotle's Lost WorksThe Soul of a Mortal on Earth is not "At Home," says Aristotle in his dialogue Eudemus. The story about the mantic dream of the expatriate Eudemus and his expectation that he "will return home"1 is well known. It makes clear that, in Aristotle's view, the death of the human (...) individual should be interpreted as the soul's "return to its homeland."2 This is strongly suggested by "the revelation of Silenus" which Plutarch (first century CE) passes down in a literal quotation from the Eudemus.3 It contains the theme of human life on earth as a punishment (timôria). The motif of human life as a punishment is central to two texts by Iamblichus (250-325 CE) and Augustine (354-430 CE), which are usually connected with Aristotle's Protrepticus.4 I want to examine these texts in more detail here. My intention in the following exposition is to propose a non-Platonistic explanation of these texts. In my opinion they have wrongly been read as testimonies of a "Platonistic" phase in Aristotle. The existence of such a phase in Aristotle's development has never been proved. Besides, the interpretation of these texts suffered from the fact that [End Page 289] Aristotle's De anima had also been explained in an unhistorical way since Alexander of Aphrodisias in the third century CE.2. Revising the Modern View of AristotleWe have to make a different assessment of Aristotle's contribution to the discussion on the soul compared with what was current until recently. For after W. Jaeger5 and F. Nuyens6, modern scholars became inclined to leave Aristotle's dialogues out of consideration, because they regarded them as "Platonizing." But a fundamental correction is necessary on this point.7 Jaeger led modern Aristotle studies in a wrong direction by assuming a sharp distinction between Aristotle's lost dialogue Eudemus and his surviving treatise De anima. Although nowadays Jaeger's theory for many scholars is something of a dead horse, nevertheless a real alternative has not been proposed. We still have to get rid of the consequences of the Jaegerian paradigm and develop a unitary interpretation of Aristotle's entire oeuvre. Even more consistently than O. Gigon has already done,8 we should assume that Aristotle's lost works and his surviving biological writings and De anima did not propose two (or more) different psychological theories but one and the same. Because this one Aristotelian psychology was a non-Platonistic but nevertheless dualistic psychology, we have much more reason than could be recognized in the past to assume Aristotelian influence on this discussion.On one essential issue Aristotle disagreed with his teacher Plato: the soul,9 more particularly the indissoluble bond of the soul with a body. Aristotle radically and [End Page 290] consistently argued for the distinction between nous and psychè.10 For Aristotle the nous-in-act is always wholly incorporeal. But he considered it characteristic of the soul that it cannot carry out its functions "without body."11However, the crucial question is: what body does Aristotle mean when he says that the soul cannot perform its specific activities "without body"? Jaeger and Nuyens were wholly convinced that Aristotle was referring to the visible, external body of a human being, animal, or plant. Hence they saw a yawning gap between Aristotle's views in De anima and his position in the dialogue the Eudemus. In the Eudemus Aristotle had clearly argued that the soul can perform its own functions very well, indeed better, without the galling and oppressive visible body.12 But in De anima II 1, in his famous definition of "the soul," Aristotle says that the soul is inextricably bound up with a "sôma physikon organikon."13 Jaeger and Nuyens, following an almost unanimous tradition since Alexander of Aphrodisias in the third century CE, interpreted this sentence in the sense that the soul is the formal principle or entelechy of an "organic body" or a "natural body equipped with organs," i.e., the visible body... (shrink)

Aristotle's definition of the soul should be interpreted as: 'the soul is the entelechy of a natural body that serves as its instrument'.

The work _De spiritu_ is an important but neglected work by Aristotle. It clearly shows for the first time that Aristotle assumed a special body as the ‘instrument’ of the soul. By means of this soul/body the soul forms the visible body of plants, animals and human beings.

Ernst Tugendhat's major work, Vorlesungen zur Einführung in die sprachanalytische Philosophie, was translated into English in 1982. Although trained in Heideggerian phenomenological and hermeneutical thinking, Tugendhat increasingly came to believe that the most appropriate approach to philosophy was an analytical one. This influential work grew from that conviction and brought new perspectives to some of the central and abiding questions of metaphysics and the philosophy of language. Presented in a fresh twenty-first-century series livery, and including a specially commissioned preface written (...) by Hans-Johann Glock, illuminating its enduring importance and relevance to philosophical enquiry, this impressive work has been revived for a new generation of readers. (shrink)

The cosmetics, detergents and food industries trial development products using healthy human volunteer studies. They also use human tissue for in vitro investigations. Hitherto, the ethics of such work has not been regulated. The UK Human Tissue Act will have legal implications on current arrangements for such studies within the industry, especially with regards to informed consent and seeking ethical review of research proposals. At present, however, it is unclear who will fund ethical review for use of ‘relevant material’ in (...) non-medical research, and on the required status of ethics committees to review such work. The principles behind the sampling, storage and processing of ‘relevant material’ are largely identical whether it be for medical or non-medical investigations. It is argued, therefore, that this is further justification for industry and professional bodies to adopt best practice of ethical review for all studies in ‘grey areas’ outside the scope of regulations. This would follow closely those standards applied to biomedical research. (shrink)

Издание содержит: Жанр интеллектуальной биографии в современной российской историографии; Кризис как риторическое псевдособытие в политической истории и др.